Sox2 expression defines a heterogeneous population of neurosphere-forming cells in the adult murine brain
نویسندگان
چکیده
منابع مشابه
p38a controls self-renewal and fate decision of neurosphere-forming cells in adult hippocampus
http://dx.doi.org/10.1016/j.fob.2015.05.001 2211-5463/ 2015 The Authors. Published by Elsevier B.V. on behalf of the Federation of European Biochemical Societies. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Abbreviations: DG, dentate gyrus; NSC, neural stem cells; RGL, radial glia-like cells; SGZ, subgranular zone; SVZ, subve...
متن کاملp38α controls self-renewal and fate decision of neurosphere-forming cells in adult hippocampus
Neural stem cells (NSC) from the adult hippocampus easily lose their activity in vitro. Efficient in vitro expansion of adult hippocampus-derived NSC is important for generation of tools for research and cell therapy. Here, we show that a single copy disruption or pharmacological inhibition of p38α enables successful long-term neurosphere culture of adult mouse hippocampal cells. Expanded neuro...
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ژورنال
عنوان ژورنال: Aging Cell
سال: 2005
ISSN: 1474-9718,1474-9726
DOI: 10.1111/j.1474-9726.2005.00158.x